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Stop acid before it starts. Nexium (esomeprazole) is a member of the proton pump inhibitors drug class and is commonly used for Barrett's Esophagus, Duodenal Ulcer Prophylaxis, Erosive Esophagitis, and others. The cost for Nexium oral delayed release capsule 20 mg is around $270 for a supply of 30 capsules, depending on the pharmacy you visit. This Nexium price guide is based on using the discount card which is accepted at most U. Prices are for cash paying customers only and are not valid with insurance plans. A generic version of Nexium is available, see esomeprazole prices. Print Now The free Discount Card works like a coupon and can save you up to 80% or more off the cost of prescription medicines, over-the-counter drugs and pet prescriptions. Please note: This is a drug discount program, not an insurance plan. Valid at all major chains including Walgreens, CVS Pharmacy, Target, Wal Mart Pharmacy, Duane Reade and 65,000 pharmacies nationwide. Nexium offers may be in the form of a printable coupon, rebate, savings card, trial offer, or free samples. Nexium is a proton pump inhibitor medication prescribed to treat GERD, stomach ulcers and heartburn. It may also be used to prevent ulcers in patients who regularly take NSAIDs. Nexium works by inhibiting the production of stomach acid. To lower the price of Nexium in your pharmacy, take advantage of our Nexium coupons. Most of our coupons are printable and can get you as much as 75% off the retail price. Continue reading to learn more about Nexium and our coupons. The Nexium manufacturer coupon is a Nexium savings card that can reduce your monthly drug cost to as little as $15. Clicking on this coupon will take you to the manufacturer’s site where you will sign up to get your savings card. 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