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Xenical comes as 120 mg pills and needs to be taken with a complete glass of water. Xenical For Sale. Xenical Prices. Each turquoise capsule, with "Roche Xenical 120" printed in black ink, contains 120 mg of orlistat. Nonmedicinal ingredients gelatin, indigo carmine. Orlistat belongs to a class of medications known as anti-obesity agents, specifically gastrointestinal lipase inhibitors. When combined with a mildly reduced-calorie diet that contains no more than 30% of calories from fat, orlistat is used to help obese people lose weight and maintain weight loss. Lipase is an enzyme that is needed to breakdown dietary fats into fatty acids, which is the form of fat that gets absorbed. Orlistat blocks the action of lipase and therefore prevents dietary fat from being absorbed. At the recommended dose, orlistat inhibits dietary fat absorption by approximately 30%. 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