These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Chloroquine resistance in china Plaquenil dosing by weight For the Consumer. Continuing ringing or buzzing or other unexplained noise in the ears. feeling of constant movement of self or surroundings. irritability. nausea. nervousness. nightmares. sensation of spinning. shakiness and unsteady walk. uncontrolled eye movements. unsteadiness, trembling, or. Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia. Plaquenil side effects Get emergency medical help if you have signs of an allergic reaction to Plaquenil hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. If you notice any other effects, check with your healthcare professional. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Plaquenil 200 mg tablets side effects Hydroxychloroquine Oral Route Proper Use - Mayo Clinic, Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria Plaquenil ototoxicityChloroquine antigen presentation Side-effects aren't common. However, in some people hydroxychloroquine can cause skin rashes, especially those made worse by sunlight. feeling sick nausea or indigestion. diarrhoea. headaches. bleaching of the hair or mild hair loss. tinnitus ringing in the ears Hydroxychloroquine Side-effects, uses, time to work. Plaquenil Uses, Dosage & Side Effects -. Hydroxychloroquine Plaquenil. Hydroxychloroquine may not prevent malaria in all cases. If you experience fever or other symptoms of illness, seek immediate medical attention. You may need a different medication. Avoid exposure to mosquitoes. See also Notes section. SIDE EFFECTS Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Hydroxychloroquine side effects may vary greatly from very mild side effects that go away with time to severe side effects like eye damage, ear damage, or heart problems. Some side effects may be experienced as the body adjusts to hydroxychloroquine but may diminish as the body becomes used to the drug. Common side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss.