Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take hydroxychloroquine with all of your drugs and health problems. Hydroxychloroquine for sle Plaquenil guidelines 2016 Chloroquine spc Alcohol significantly increases the risk for liver damage while taking methotrexate, so alcohol should be avoided while on this medication”. Some patients may ignore strict advice on limiting or avoiding alcohol, or seek to avoid drugs that might curtail their alcohol intake, which in turn might deny them access to efficacious drugs 1. Methotrexate is a disease-modifying anti-rheumatic drug DMARD that is used to reduce the swelling and pain associated with certain diseases like rheumatoid arthritis, psoriatic arthritis, vasculitis, juvenile arthritis and lupus. More and more doctors are using methotrexate to treat lupus when antimalarials like hydroxychloroquine Plaquenil or nonsteroidal anti-inflammatory drugs aren’t. Hydroxychloroquine brand namePlaquenil is a disease-modifying anti-rheumatic drug DMARD approved for adults with RA. It is often given in combination with methotrexate and sulfasalazine a treatment known as triple therapy, to help slow RA disease progression for patients who do not get relief from methotrexate therapy alone. 1,2 For all uses of hydroxychloroquine: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor. Methotrexate plaquenil alcohol Common Questions About Taking Methotrexate for Rheumatoid., Methotrexate - Kaleidoscope Fighting Lupus Chloroquine nightmaresChloroquine drug adverse effects Find patient medical information for Hydroxychloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Hydroxychloroquine Oral Uses, Side Effects, Interactions.. Treatments for Rheumatoid Arthritis. Can I take Plaquenil and drink alcohol? - Page 6. I went on 15mg methotrexate per week and 400mg plaquenil per day. Within 6 weeks all symptoms were gone, returning only twice when I was having non-related health issues that challenged my immune system. Never had drug side effects except occasional nausea; my hair has thinned but I'm in my 60's so its to be expected. There's no known interaction between alcohol and hydroxychloroquine. However, if you're also taking methotrexate you should keep well within the recommended limits no more than 14 units of alcohol per week for adults as methotrexate can interact with alcohol and affect your liver. In some circumstances your doctor may advise lower limits. We compare the side effects and drug effectiveness of Plaquenil and Methotrexate. The study is created by eHealthMe based on reports of 385,604 people who take Plaquenil and Methotrexate, and is updated regularly. eHealthMe has been monitoring drugs since 2008. Our original studies are referenced on 600+ peer-reviewed medical publications.