Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil treatment for alopecia Is plaquenil retinal toxicity reversible How frequent is vision loss from plaquenil Plaquenil how fast to start working. deleted_user 05/12/2011. Hi To answer someone's question I am in my late 50's Was diagnosed March 2010 and started treatment. Nov. 2009 I went to my doctor complaining about stiff and swollen hands. does Plaquenil kick in quickly or. 12. 0. Leave A Reply. It takes a really long time for the Plaquenil to kick in. It may even take a year. Mine didn't start working until I was on it for 8 months and I take more than you do. I take 200 mg twice a day. I initially started at 800mg a day then dropped it to 400 mg a day. Please don't give up, you will have good days and bad days. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. How long does it take for plaquenil to kick in Plaquenil - How long to take effect?, What is the correct way to discontinue use of plaquenil? Plaquenil and dental inplantsChloroquine lysosomal degradationDo i need monthly blood test while taking hydroxychloroquine By the time I recognize that I'm getting a flare I think because I was so sick for so long I've learned to ignore it until it's too late and take my first six-pill dose of a medrol pack, it takes a good 24 hours for me to get relief. But I do automatically feel better immediately because I know relief is coming! Medrol pack. When does relief come? - Sjogren's World. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. How long did Plaquenil/Hydroxychloroquine take? DailyStrength. Donald E. Thomas Jr. MD, FACR, FACP, a practicing rheumatologist in Greenbelt, Md. and author of The Lupus Encyclopedia, regularly prescribes Plaquenil to his lupus patients. “We know that people with lupus who take their Plaquenil regularly are much more likely to live a long, normal life compared with those who don’t,” he says. Hi - I just started Plaquenil 400 mg a day two week ago and I started feeling less achy and tired a few days ago. Is it possible for it to work quicker in some people? I've heard it can take months, but I must say that I haven't felt like this since I was a kid - not achy or stiff. Has anyone had a similar Hi everyone, I was just wondering how long it took for Plaquenil to start working for you? I've been on it for about a month now, and it hasn't worked for me yet, but I know that it can take up to 4 months to kick in.