Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil maculopathy rate Chloroquine diphosphate lysosome Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis or juvenile idiopathic arthritis and other autoimmune diseases. It is not clear why hydroxychloroquine is effective at treating autoimmune diseases. Had headaches with the plaquenil so went to the sulfar and predisone. Sulfar was a waste of time and since I had a little help from the plaquenil he switched me back to that with pain meds for the headaches and body. Recently i went back for app. and plaquenil had stopped doing anything so he added the methotrexate to it. I did not want to take it. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Specifically, anti-malarial medications have shown to improve muscle and. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Which autoimmune not treat with plaquenil Plaquenil Use in Autoimmune Diseases, What next if plaquenil doesn't work? Plaquenil like medRetinal damage plaquenilPlaquenil et fatigueConcurrent administration of chloroquine It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Fear of Plaquenil - Autoimmune Disorders - MedHelp. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. I was so relieved to finally be able to put a name to all that I have been dealing with for the last few years in addition to autoimmune thyroid disease for the last six years, but I am also sort of hesitant to start the Plaquenil, for fear of the possible side effects. Hydroxychloroquine or Plaquenil It is part of a series of medications that were originally used to prevent and treat malaria, but, at present, it is used for discomforts such as rheumatoid arthritis, some symptoms of lupus and other autoimmune diseases. It has also been used to prevent and treat malaria. Here are the three most common antimalarial drugs prescribed for lupus Hydroxychloroquine Plaquenil This is the most commonly prescribed antimalarial. Chloroquine Aralen This drug has been known to have more serious side effects. Quinacrine Atabrine Quinacrine is another.