Plaquenil retina damage

Discussion in 'Plaquenil Generic' started by k2i, 28-Feb-2020.

  1. rebel_web Well-Known Member

    Plaquenil retina damage


    One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus.

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    Plaquenil toxicity is typically asymptomatic in early stages, but over time can lead to severe vision loss and retinal damage. The risk of retinal toxicity was initially believed to be less than 1% after long-term or a cumulative dosage of 1,000mg. 3 The toxicity would double by 10 years, resulting in a 20% prevalence after 20 years. 4. The mechanism of hydroxychloroquine retinal toxicity has yet to be fully elucidated. Studies have shown that the drug affects the metabolism of retinal cells and also binds to melanin in the RPE, which could explain the persistent toxicity after discontinuation of the medication. Screening requires the use of tests, such as 10–2 visual fields and SD-OCT and other modern techniques, such as autofluorescence imaging and multifocal electroretinography, to demonstrate early retinal damage.” 1 Melles & Marmor. The Risk of Toxic Retinopathy in Patients on Long-term Hydroxychloroquine Therapy.

    It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress.

    Plaquenil retina damage

    Has anyone experienced plaquenil toxicity with damage to eyes?, Hydroxychloroquine-Induced Retinal Toxicity - American.

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  5. She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine Plaquenil 200mg bid 6.5mg/kg for 10 years, which was stopped one year prior to presentation.

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    Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Jun 13, 2019 What happens if retinal damage is found? If your ophthalmologist finds any signs of retinal damage, he or she will tell your primary care doctor or inflammatory disease specialist to stop Plaquenil treatment immediately. Plaquenil-induced toxicity usually will not occur before five years of taking the drug. “Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs.

     
  6. mininet Guest

    Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Hydroxychloroquine An old drug with new relevance. Hydroxychloroquine usage in US patients, their experiences of. PATIENT FACT SHEET Hydroxychloroquine Plaquenil
     
  7. Ognejar XenForo Moderator

    Plaquenil Side Effects - GoodRx Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

    Plaquenil Side Effects on Your Eyes and Vision
     
  8. auto-car-usa Moderator

    Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA 1. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over.

    How Does Plaquenil Work For Rheumatoid Arthritis