Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Effects of stopping plaquenil Plaquenil side effects mood changes High risk medication use plaquenil Depression is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Enbrel, and have Pain. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. Hydroxy Plaquenil CAN affect moods & can cause 'mental changes' in some people u should b able 2 clarify this by reading u're info leaflet in the med packet. I came off hydroxy as I gained no benefit whatsoever & apart from getting near on every side effect from it, became the most s**** bitch ever lol! Nov 18, 2013 Bad Side Effects of Plaquenil. I have been recently diagnosed with Lupus about 4 months ago and have started plaquenil with the hope it would relieve my symptoms no energy, achy body and severe hair loss. It seems as though it has helped the first two symptoms, but I have horrible constipation. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Side effects of plaquenil depression Depression in Plaquenil how severe and when it was., Does Plaquenil affect your temperament? - LUPUS UK Chloroquine and proguanil boots priceAralen canadaDress syndrome hydroxychloroquineHydroxychloroquine retinopathy side effectsCan you get plaquenil in a injection Less common side effects Skin rashes or changes in skin color; Thinning hair; Weakness; Irregular heartbeat; Mental/mood changes; Arm/leg/back pain; Anxiety; Depression; Ringing in the ears or hearing loss; Worsening of skin conditions If you have psoriasis, Plaquenil may make your condition worse. Talk to your doctor if you have this condition. Rare side effects Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Bad Side Effects of Plaquenil -. PLAQUENIL Side Effects, Reviews by Patients -. Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells anemia. Tell your doctor if you experience serious side effects of Plaquenil including muscle weakness, twitching, uncontrolled movement, loss of balance or coordination, blurred vision, light sensitivity, seeing halos around lights, pale skin, easy bruising or. bleeding, confusion, unusual. This study is created by eHealthMe based on reports of 1,993 people who have side effects when taking Plaquenil from sources other than FDA, and is updated regularly. On eHealthMe, you can check your drugs with millions of FDA reports, or become a member to prevent side effects and save money.