We won't sell or give your information to anyone else, and you can unsubscribe at any time. Please select ONE category from the email lists that best describes your interest in macular degeneration. Plaquenil causes lowcalcium levels How long do you take chloroquine Difference between chloroquine and primaquine Plaquenil side effects increased appetitie Aug 16, 2012 I am newly "diagnosed", though still waiting for it to be official. Haha! Anyway I was diagnosed with dry macular degeneration 7 years ago. A recent exam showed it has worsened. I have also seen 3 rheumatologists, and 2 of them say I should take Plaquenil and the risk of damage to my macula is not big enough to not take the Plaquenil. One. Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. The characteristics of patients which may increase of developing toxicity symptoms while taking Plaquenil include an age of more than 60 years old, having renal or hepatic insufficiency or any existing macular degeneration and retinal disease. Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. A 45-year-old black female presented with no ocular or visual complaints. However, her medical history was significant for a recent diagnosis of lupus. Plaquenil and macular degeneration The Risk of Retinal Toxicity with Plaquenil, Hydroxychloroquine Plaquenil Toxicity and Recommendations. Chloroquine and adverse drug eventsQuinoric or plaquenilRash with plaquenilPlaquenil maculopathy cumulative dosePlaquenil hair Aug 06, 2014 Thus, ophthalmoscopy alone is not sufficient to screen for HCQ toxicity. 7,8 That being said, a detailed anterior and posterior segment examination to assess for corneal verticillata as well as concurrent macular disease i.e. age-related macular degeneration, remains important in monitoring these patients long term. Multimodal Imaging in Plaquenil Toxicity. Plaquenil Toxicity - Symptoms, Treatment, Risk Factors.. Macular degeneration and lupus" Lupus Community - Support Group. Focus on Eyes Long-term Plaquenil intake can affect your vision. by Dr. Juan Carlos de Rivero Vaccari and Dr. Frederick Ho, Special to FLORIDA TODAY. Plaquenil, or hydroxychloroquine, is an anti-malaria medication that is commonly used to treat autoimmune disorders like lupus or rheumatoid arthritis. With all of the physical and emotional complications that lupus can cause, it’s easy to overlook symptoms that seem minor at first. But take this advice Don’t ignore changes in vision. While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage. Sep 15, 2014 Hydroxychloroquine sulfate HCQ, Plaquenil is an analogue of chloroquine CQ, an antimalarial agent, used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune disorders. Its use has been associated with severe retinal toxicity, requiring a discontinuation of therapy.