The ankles and legs are common sites of swelling because of gravity’s effect on the fluids in the human body. However, fluid retention from gravity isn’t the only cause of a swollen ankle or leg. Chloroquine phosphate tablets ip 250 mg Does plaquenil cause kidney damage I have already decided to stop taking it until I can speak with my rheumy. I have another medical condition that could cause this severe back pain. I'm thinking this is likely a coincidence that I developed this problem right after starting the Plaquenil. Also, does anyone know what typr of muscle damage Plaquenil can cause? The ankles and legs are common sites of swelling because of gravity’s effect on the fluids in the human body. However, fluid retention from gravity isn’t the only cause of a swollen ankle or leg. Swollen ankles, or edema, are a common symptom of a variety of conditions. Learn more about the causes of swollen ankles, including lymphedema, pregnancy, cellulitis, and blood clots, here. We. A swollen ankle or leg can cause the lower part of the leg to appear larger than normal. It may be painful, with the skin over your leg feeling tight and stretched out. Injuries and subsequent inflammation can also cause fluid retention and swelling. Can swollen ankles be caused by hydroxychloroquine Swollen legs and ankles 8 causes and their treatment, Swollen Ankle and Leg Causes, Treatments, and More Plaquenil sleepChloroquine diphsophateHypoglycemia due to maternal plaquenilHalf life of chloroquine It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works. How to use Plaquenil Hydroxychloroquine is usually taken with food. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Swollen ankles 12 causes and how to treat them. Foot, leg, and ankle swelling and drugs with ingredients of.. Management of vasculitis associated with SS. Hyperglobulinemic purpura may be managed using symptomatic therapy. Avoidance of tight fitting elastic on the lower extremities, elimination of long periods of standing and elevation of one’s legs while sitting are all helpful in reducing elevated hydrostatic pressure. Estrogen can increase your risk of a blood clot in the leg deep vein thrombosis, which can cause one-sided leg swelling. This is an urgent medical issue. However, estrogen can also cause swelling in both legs, which is usually not an emergency. If you notice swelling and you’re taking a birth control pill, be sure to seek medical attention. Swollen Outer Ankle Symptoms, Causes & Common Questions. If the outside of your ankle is swollen, this may be caused by trauma from an injury, ankle arthritis, or posterior tibialis tendinopathy. Read now for more information on swelling on outside of the ankle and treatment options.