It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Does plaquenil work Total synthesis of chloroquine Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Currently as I'm writing this am having the same symptoms you describe under my feet, it started about 4-5 months ago, were swelling of the lips, tongue and side of the mouth swells up, and most recently started to get the swelling under my feet with the same description you noted, also my hand and my wrist, all these caused an itching feeling and felt very warm to touch and is difficult to. Provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Taking plaquenil and hands still swollen Swollen feet and plaquenil Anti-Inflammatories discussions., Sudden unexplained swelling, hands, feet, lip, wrists Other. Plaquenil for energyHydroxychloroquine instructionsWhy is the drug hydroxychloroquineLupus hair loss plaquenilWho can do plaquenil baseline test Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. Plaquenil Uses, Dosage & Side Effects -. Plaquenil Side Effects Common, Severe, Long Term -. Prednisone/Plaquenil question -. Is hydroxychloroquine Plaquenil safe to take if I'm pregnant or breastfeeding? Hydroxychloroquine should only be used in pregnant women for malaria prophylaxis or treatment. Hydroxychloroquine may be secreted in breast milk and may cause side effects in the infant. I was put on three anitibotics that did not help, then placed on prednisone for three months and in December started taking Plaquenil. After the Plaquenil the swelling under my arm went down. However, the lump in my shoulder has not. It causes a burning sensation in the muscle on the back of my shoulder also. How to use Plaquenil. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight.