Please review the following URL and make sure that it is spelled correctly. Hi everybody, I was wondering if Plaquenil's primary mode of action was to suppress the immune system? Is plaquenil safe to use Chloroquine and proguanil buy online Plaquenil side effects fluid retention A recent large study of people with cardiovascular disease found that hydroxychloroquine Plaquenil does not increase the risk of infection and methotrexate increases the risk of infection only slightly. The concern with immune suppression is that the virus could replicate more freely and cause more severe or extensive disease, says Dr. Winthrop. Re want to know good stuff about plaquenil Sorry to be a party pooper here, but I have been on Plaquenil for 5 months and can't say I feel any difference at all. If anything I am sleeping all day but for just about 1 1/2 hours at a time. Methotrexate does suppress the immune system, but serious infections with methotrexate are not common. Your rheumatologist will monitor you closely for any side effects associated with methotrexate such as liver test abnormalities, pneumonitis, or infections. Almost all autoimmune diseases require the immune system be suppressed to some degree. 1 month ago and prior to taking it I rarely ever got sick with colds,flu etc. I am asking this question, because I started this med approx. Plaquenil and immune system Will you have Immune system disorder with Plaquenil - eHealthMe, Immune & Autoimmune - Lupus want to know good stuff about plaquenil Plaquenil allergic rash does it burnPlaquenil and macular pucker2 hydroxychloroquine sulfate plaquenil sulfateFlomax and plaquenil There is evidence that hydroxychloroquine may interfere with communication between cells in the immune system. This action suppresses the normally overactive immune response in lupus patients which may explain one reason Plaquenil works so well for those suffering with lupus. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Methotrexate Does it weaken my immune system?. What does hydroxychloroquine do to immune system - Answers on.. RA is a systemic autoimmune disease in which the immune system attacks the joints and can affect other parts of the body.1 Several drugs to treat RA -- biologics Enbrel, Humira, etc. and DMARDS Plaquenil, methotrexate suppress the immune system.2 Suppressing the immune system helps slow or prevent damage to joints and other body systems. Any one have any experience or info regarding pre-existing precancerous conditions and the effects of Plaquenil on the immune system. I see so much info on the net where some says that Plaquenil has very mild effect on immune system except for eye issues --- Other info says it is an immunosuppressant. Yes, Plaquenil suppresses the immune system. Autoimmune disease such as Sjogrens occurs when the body gets "confused" and attacks healthy tissue instead of just attacking the germs. Basically, the immune system is a bit out of control. Plaquenil works by suppressing the immune system.