While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. "I started the hydroxychloroquine medication a week ago and within the first day or two noticed a big difference in my pain and fatigue with major improvement SLE. Chloroquine for restless leg syndrome Quitting plaquenil Pronounce hydroxychloroquine When was chloroquine invented Fatigue is one of the most common symptoms of fact, most people with lupus have fatigue at some point in their illness. “When lupus hit, it was like running into a wall at 80 mph. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as. Hi Phoebe, I have been on plaquenil for many years and have not experienced a sudden onset of fatigue after taking it. While those of us with lupus never truly find anything to relieve fatigue, plaquenil is suppose to help with fatigue rather than create more from what I understand. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Fatigue plaquenil Long-Term Side Effects of Plaquenil for Rheumatoid., Plaquenil Hydroxychloroquine - Side Effects, Dosage. Hydroxychloroquine plaquenil pharmacological drug classPlaquenil empty stomachHistory of plaquenilPlaquenil for mild rheumatoid arthritis I started on the Plaquenil a little over a week ago. Not much in the way of side effects. Some minor stomach stuff but that could be normal and not related to the Plaquenil. I started at 200mg and increased to 400mg after a week. Andie213, my fatigue has been frustrating for me as well. Experiences taking Plaquenil for Fatigue and Muscle Pain.. Does Plaquenil make you tired? DailyStrength. PATIENT FACT SHEET Hydroxychloroquine Plaquenil. Plaquenil Side Effects by Likelihood and Severity INFREQUENT side effects. If experienced, these tend to have a Severe expression. A Disorder Of The Retina Of The Eye; My joints swell, fatigue, mouth and eyes are dry, ulcers in my mouth and nose, sun sensitivity, Raynaud's, rashes etc. My rheumatologist put me on Plaquenil and just said "this is the medication we use when people have symptoms like yours", but then say I don't have Lupus, RA or Sjogren's! I see a number of other specialists for my other symptoms. I have been on Plaquenil for years. It has not helped me with fatigue. Things like vitamins and exercise might assist with decreasing the fatigue level. I have been on 2 Dmards and a biologic for the longest time. I also take Tramadol for pain and now Indomethicin has been added to the mix to help with stiffness.