Plaquenil renal toxicity

Discussion in 'Chloroquine 250' started by nevalineru, 16-Mar-2020.

  1. DOMOBOY Moderator

    Plaquenil renal toxicity


    One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus.

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    Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. Hydroxychloroquine sulfate HCQ, Plaquenil is an analogue of chloroquine CQ, an antimalarial agent, used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune disorders. Its use has been associated with severe retinal toxicity, requiring a discontinuation of therapy. Renal ischemia/reperfusion I/R injury, the major cause of acute kidney injury AKI, is associated with severe morbidity and mortality in both developing and developed countries. Accumulating evidence has suggested that inflammation plays a critical role in the pathology of ischemic injury.

    It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress.

    Plaquenil renal toxicity

    Hydroxychloroquine Plaquenil RheumTutor, Retinal toxicity associated with chronic exposure to hydroxychloroquine.

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  6. PLAQUENIL with drugs known to induce retinal toxicity, such as tamoxifen, is not recommended. Careful ophthalmologic examination should be more frequent and adapted to the patient, in the

    • Plaquenil Hydroxychloroquine Sulfate - Sanofi.
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    This occurs when melanin is able to bind to the “High Risk Medication” Plaquenil within the Retinal Pigment Epithelium RPE as well as direct toxicity to retinal ganglion cells. The drugs ability to bind to these pigmented cells creates a “Bulls Eye” around the macula, giving it this very unique appearance. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including rash, itching/swelling especially of the face/tongue/throat, dizziness, trouble breathing. This is not a complete list of possible side effects. Lupus is an autoimmune disease that can affect almost any part of your body, most often your joints, skin, kidneys, heart, lungs, blood, or brain. Your two kidneys are part of your renal system, which also includes two ureters, the bladder, and the urethra. As the primary organs of the renal system, your kidneys are responsible for

     
  7. Suriko XenForo Moderator

    tags Modify this file to add javascript or css files for your page from customize/static folder Jinja2 (which is template engine) is not allowed to use here. Plaquenil Oral Uses, Side Effects, Interactions. Had to stop taking Plaquenil - What If I Stop Taking Allopurinol? Get Rid Of Gout
     
  8. lesio Well-Known Member

    Favorable Effect of Hydroxychloroquine in Patients with Rheumatoid. Background/Purpose Hydroxychloroquine HCQ is widely prescribed for patients with Rheumatoid Arthritis RA and Systemic Lupus Erythromatus SLE. It is fairly well tolerated with multiple well studied side effects, including those on insulin homeostasis and glucose metabolism.

    Unmet needs in rheumatoid arthritis Arthritis Research.
     
  9. wqeassxz Well-Known Member

    The Nine Lives of Hydroxychloroquine RheumNow. The Nine Lives of Hydroxychloroquine By Martin J. Bergman, MD. By the 1940s, quinine, or rather its derivative chloroquine, was recognized for its anti-malarial properties and found use among troops fighting in the Pacific during WW-II. However, it was noted that this compound had significant toxicities. In 1945, a modification.

    Chloroquine Oral Uses, Side Effects, Interactions.