Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Leflunomide methotrexate and hydroxychloroquine Plaquenil nausea reddit Methotrexate can sometimes cause side effects, which may include feeling sick; headaches; vomiting; diarrhoea; shortness of breath; mouth ulcers; minor hair loss and hair thinning; rashes. If you have severe side effects, you should contact a health professional for advice. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about. Find information about common, infrequent and rare side effects of Methotrexate Anti-Rheumatic Oral. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Methotrexate and plaquenil side effects Quitting methotrexate and plaquenil - Autoimmune Disorders., Methotrexate Oral Route Side Effects - Mayo Clinic Hydroxychloroquine pharmacotherapyIs plaquenil used for mixed connectivity tissue disorder Consumer information about the medication HYDROXYCHLOROQUINE - ORAL Plaquenil, includes side effects, drug interactions, recommended dosages, and storage information. Read more about the prescription drug HYDROXYCHLOROQUINE - ORAL. HYDROXYCHLOROQUINE - ORAL Plaquenil side effects, medical.. Common and Rare Side Effects for Methotrexate Anti-Rheumatic.. Ocular side effects of anti-rheumatic medications what a.. Hydroxychloroquine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away headache; dizziness; loss of appetite; nausea; diarrhea; stomach pain; vomiting; skin rash; If you experience any of the following symptoms, call your doctor immediately Medication side effects Two patients experienced medication side effects. One 6.7% in methotrexate group who showed elevated liver enzymes and the other 7.1% in hydroxychloroquine group who demonstrated drug eruption. Methotrexate vs plaquenil side effects long term and short term The only problem is the Plaquenil causes severe headaches that interfer with my daily activities also. But the Dr suggested I try Methotrexate instead.