Most people develop psoriasis first and are later diagnosed with psoriatic arthritis, but the joint problems can sometimes begin before skin patches appear. Joint pain, stiffness and swelling are the main signs and symptoms of psoriatic arthritis. Hydroxychloroquine plaquenil weight gain Plaquenil well tolerated Conversely, patients can have psoriasis for over 20 years prior to the development of arthritis, leading to the ultimate diagnosis of psoriatic arthritis. Psoriatic arthritis is a systemic rheumatic disease that also can cause inflammation in body tissues away from the joints other than the skin, such as in the eyes, heart, lungs, and kidneys. Summary. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. January 8, 2013 " I was diagnosed 10 years ago with Psoriatic Arthritis and have tried many different treatments including Plaquenil. The only thing that has helped, although slightly, is Humira. I cannot take methotrexate because I have a fatty liver and methotrexate is tough on the liver. In both psoriasis and psoriatic arthritis, disease flares may alternate with periods of remission. They can affect any part of your body, including your fingertips and spine, and can range from relatively mild to severe. Can plaquenil cause psoriatic arthritis Hydroxychloroquine Plaquenil, Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria Plaquenil and neuropathy I know I had never heard of it until my rheumatologist said that is what I have.along w/osteoarthritis and fibromyalgia. So, he started me on 400 mg of Plaquenil a day and he just upped it to 600 mg a day. I take tramadol for pain. My left wrist is constantly swollen now. Inflammatory Osteoarthritis And Plaquenil. Plaquenil and Psoriatic Arthritis - Reviews. Taking Plaquenil for Rheumatoid Arthritis. May 21, 2003 ** Originally posted by joannapw **. Has anyone had experience with Plaquenil Hydroxychloroquine as treatment for psoriatic arthritis? I am new to this struggle and my MD is trying to be rather conservative because severe hypothyroidism is complicating my symptoms. Hydroxychloroquine is commonly used alongside other disease-modifying drugs including methotrexate – especially for rheumatoid arthritis. However, some drugs can interact with hydroxychloroquine. Indigestion remedies for example, antacids including some over-the-counter preparations can stop hydroxychloroquine being absorbed. Jul 03, 2018 Psoriatic arthritis. Psoriatic arthritis is an autoimmune condition in which your immune system attacks joint and skin cells and causes joint inflammation, and over time, can also trigger joint.