Chloroquine torsades

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  1. kleerzapa Guest

    Chloroquine torsades


    It is a polymorphic ventricular tachycardia that exhibits distinct characteristics on the electrocardiogram (ECG). Symptoms and consequences include palpitations, dizziness, lightheadedness (during shorter episodes), fainting (during longer episodes), and sudden cardiac death. Torsades occurs as both an inherited (linked to at least 17 genes) Common causes for torsades de pointes include drug-induced QT prolongation and less often diarrhea, low serum magnesium, and low serum potassium or congenital long QT syndrome.

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    Erythromycin is a macrolide antibiotic that is widely used for various infections of the upper respiratory tract, skin, and soft tissue. Similar to other macrolides clarithromycin, azithromycin, erythromycin has been linked to QTc interval prolongation and torsade de pointes TdP arrhythmia. The risk of torsades de pointes probably also varies with the type of drug irrespective of the effect on the QT interval. The absolute risk of torsades de pointes for sotalol and quinidine Kinidine appear higher than those associ-ated with amiodarone, although all three drugs cause marked QT pro-longation. The risks of torsades de pointes Nov 25, 2019 Chloroquine is an anti-malaria medicine that works by interfering with the growth of parasites in the red blood cells of the human body. Parasites that cause malaria typically enter the body through the bite of a mosquito.

    Certain drugs and combinations of drugs resulting in drug interactions are common contributors to torsades de pointes risk. It can be seen in malnourished individuals and chronic alcoholics, due to a deficiency in potassium and/or magnesium.

    Chloroquine torsades

    Chloroquine Dosage Guide with Precautions -, Causes and management of torsades de pointes

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  5. Torsade de pointes is an uncommon and distinctive form of polymorphic ventricular tachycardia VT characterized by a gradual change in the amplitude and twisting of the QRS complexes around the isoelectric line see the image below. Torsade de pointes, often referred to as torsade, is associated with a prolonged QT interval, which may be co.

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    In small children, the ingestion of 1-2 tablets of chloroquine is a potentially life-threatening ingestion. Chloroquine is on the list of ‘two pills that can kill‘ toddlers. The worst case scenario is an ingestion of 310mg/15kg = ~21 mg/kg. In general 10mg/kg is considered toxic, with increasing mortality at doses 30mg/kg. Find patient medical information for Chloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Foscarnet has been associated with postmarketing reports of both QT prolongation and torsade de pointes TdP. Chloroquine administration is also associated with an increased risk of QT prolongation and TdP. If these drugs are administered together, obtain an electrocardiogram and electrolyte concentrations before and periodically during treatment.

     
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