Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Medication for rheumatoid arthritis plaquenil Plaquenil long term Chloroquine glutathione synthase Hydroxychloroquine is effective at treating autoimmune diseases. It is believed that hydroxychloroquine interferes with communication of cells in the immune system. SIDE is rare. It is recommended that you have an eye exam EFFECTS HOW TO TAKE IT Hydroxychloroquine comes in an oral tablet. Adult dosing ranges from 200mg or 400mg per day 5 mg per Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes. Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil eye effects Taking Plaquenil for Rheumatoid Arthritis, Plaquenil Hydroxychloroquine - Side Effects, Dosage. Plaquenil bloodshot eyesPlaquenil eye toxicity symptomsHydroxychloroquine win side effectsPlaquenil macula Inability to move the eyes increased blinking or spasms of the eyelid joint or muscle pain large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, and sex organs loss of hearing lower back or side pain noisy breathing painful or difficult urination red irritated eyes Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Protecting your eyesight when taking Plaquenil Lupus.. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Some diseases treated with Plaquenil include Lupus, which causes fever, rashes, skin problems, and other symptoms. Rheumatoid arthritis, a condition that causes pain and swelling in the joints of your hands and feet. Sjögren’s syndrome, which causes dry eyes and dry mouth. Plaquenil lowers your immune system’s ability to cause inflammation. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. While today it is used to treat autoimmune conditions, such as rheumatoid arthritis and lupus, it was originally used as an anti-malaria drug. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have had any eye changes or changes in eyesight due to hydroxychloroquine or drugs like this one. If you have psoriasis.