In many cases, once the offending drug has been stopped, fading of the lesions occurs. However, the pigmentation may last a long time or become permanent. Plaquenil and brain dizziness Hydroxychloroquine dosage rheumatoid arthritis Hydroxychloroquine shingles Dec 15, 2017 One such sign is hyperpigmentation, a sign from your skin that all is not well within your body. Hyperpigmentation is a dermatological condition when the getting discoloured and darkened in places. Applies to hydroxychloroquine oral tablet Along with its needed effects, hydroxychloroquine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. PLAQUENIL is indicated for the treatment of chronic discoid lupus erythematosus and systemic lupus erythematosus in adults. Rheumatoid Arthritis. PLAQUENIL is indicated for the treatment of acute and chronic rheumatoid arthritis in adults. Skin, the largest organ of the human body, is a mirror of your health. Because many drugs that induce skin pigmentation also cause photosensitivity reactions, sun protection is usually recommended. Plaquenil associated hyperpigmentation Hydroxychloroquine-Associated Hyperpigmentation. - PubMed Central PMC, Hydroxychloroquine Side Effects Common, Severe, Long Term - Scholarly articles plaquenil autoimmune encep halitisHydroxychloroquine plaquenil scdPlaquenil skin cha gesWhen to take plaquenilHydroxychloroquine seizures Aug 14, 2013 A skin biopsy of the patient’s dyschromia confirmed the diagnosis of hydroxychloroquine-associated hyperpigmentation. Conclusion Hyperpigmentation of skin, mucosa, and nails can be observed in patients treated with antimalarials, including hydroxychloroquine. Hydroxychloroquine-Associated Hyperpigmentation Mimicking.. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Hydroxychloroquine toxicity - EyeWiki. Using multivariate logistic regression, we found that HCQ-induced pigmentation was independently associated with previous treatment with oral anticoagulants and/or antiplatelet agents and with higher blood HCQ concentration. Conclusions and Relevance Hydroxychloroquine-induced pigmentation is not a rare adverse effect of HCQ. Our data support the hypothesis that HCQ-induced pigmentation is secondary to ecchymosis or bruising. Hydroxychloroquine Plaquenil is an older DMARD sometimes still used for mild RA. It may work by interrupting signaling among cells. It’s one of the best tolerated DMARDs. Side effects are usually mild and may include nausea and diarrhea. Taking the drug with food may help. Changes to the skin are less common. Plaquenil and Skin hyperpigmentation - from FDA reports Summary Skin hyperpigmentation is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Omniscan, and have Arteriogram.