Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Grapefruit and plaquenil What is hydroxychloroquine sulphate used for Plaquenil side effects dreams Hydroxychloroquine HCQ; Plaquenil is used increasingly in the management of a variety of autoimmune disorders, with well established roles in dermatology and rheumatology and emerging roles in. Hydroxychloroquine Maculopathy An Update on Screening and Diagnosis A brief guide for imaging SHIRI SHULMAN, MD. H ydroxychloroquine HCQ; Plaquenil, Sanofi, Bridgewater, NJ is an antimalarial agent that is also commonly used as a treatment for a variety of rheumatologic and dermatologic conditions, such as rheumatoid arthritis and systemic lupus erythematosus. Provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). What must be evaluated while on hydroxychloroquine Drug spotlight on hydroxychloroquine Lupus Foundation of., Retinal Physician - Hydroxychloroquine Maculopathy An Update on. Hydroxychloroquine efectos secundarios Hydroxychloroquine sulfate is a colorless crystalline solid, soluble in water to at least 20 percent; chemically the drug is 2-4-7-Chloro-4-quinolylaminopentylethylamino ethanol sulfate 11. PLAQUENIL hydroxychloroquine sulfate tablets contain 200 mg hydroxychloroquine sulfate, equivalent to 155 mg base, and are for oral administration. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Hydroxychloroquine Professional Patient Advice -. Hydroxychloroquine, anti-malarial drug, tapped for.. Has shown that hydroxychloroquine has a beneﬁcial effect in inducing renal remission in membranous lupus nephritis in combination with mycophenolate as the initial therapy.43 A Canadian randomised, double-blinded, placebo-controlled trial evaluated the effects of withdrawing hydroxychloroquine in 47 patients with clinically stable However, such vacuoles may also be seen in acid maltase deficiency, inclusion body myositis, and some muscular dystrophies, and while these conditions were not suspected in the 8 reported cases here, other diagnostic possibilities must also be taken into consideration. Hydroxychloroquine is still a safe and beneficial drug for use in rheumatic diseases. Retinal toxicity is unpredictable and can occur even at relatively low doses of hydroxychloroquine. There are new screening modalities for early detection of asymptomatic hydroxychloroquine ocular toxicity.