Its cause is not known, and most episodes of granuloma annulare clear up after a few years, with or without treatment. Although granuloma annulare can occur in people of any race and at any age, it is most commonly seen in children and young adults. Plaquenil kidney pain Chloroquine aralen There are other less common forms of granuloma annulare Generalised granuloma annulare 8-15% of cases. Adults are more commonly affected. It is characterised by widespread small bumps or discoloured patches of skin, with a tendency to present on the trunk. Subcutaneous granuloma annulare is rare. It is more commonly seen in children. Erythema annulare centrifugum typically presents as annular patches with trailing scale inside erythematous borders. Differential Diagnosis of Annular Lesions. chloroquine, methotrexate. Chloroquine and its congeners can cause two typical adverse effects in the eyes keratopathy and retinopathy. Both of these effects are associated with the administration of the drugs over long periods of time. Chloroquine-induced keratopathy is limited to the corneal epithelium, where high concentrations of the drug are usually used. The lesions of granuloma annulare are usually found in the same areas on both sides of the body (symmetrically). Females are slightly more likely than males to develop granuloma annulare. Chloroquin andgranuloma annulare Granuloma Annulare - Pictures, Causes, Contagious, Symptoms, Treatment., Differential Diagnosis of Annular Lesions - American Family. Hydroxychloroquine blood tests If you have a type of granuloma annulare that covers a large area of your body or causes a deep growth in your skin, your dermatologist may recommend treatment. Treatment may also be an option if you have noticeable patches and dislike how your skin looks. If you have a few noticeable patches. Granuloma annulare Diagnosis and treatment. Chloroquine analogues in drug discovery new directions of uses.. Plaquenil and granuloma annulare - Dermatology - MedHelp. Treatment of generalized granuloma annulare with low-dose hydroxychloroquine Article in Korean Journal of Dermatology 459969-972 September 2007 with 719 Reads How we measure 'reads' Granuloma annulare GA is skin disorder that most often causes a rash with red bumps erythematous papules arranged in a circle or ring pattern annular. GA is not contagious and is not cancerous. The rash may be localized or generalized. What is granuloma annulare? Granuloma annulare is a long-term chronic skin disease consisting of a rash with reddish bumps arranged in a circle or ring.