One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Effects of plaquenil on liver Chloroquine brands Hydroxychloroquine sulfate generic Plaquenil safe in pregnancy Aug 29, 2014 Plaquenil, hydroxychloroquine HCQ, is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis RA, systemic lupus erythematosus SLE and other inflammatory and autoimmune diseases. Mar 27, 2007 In patients with systemic lupus erythematosus SLE, hydroxychloroquine prevents disease flares and damage accrual and facilitates the response to mycophenolate mofetil in those with renal involvement. A study was undertaken to determine whether hydroxychloroquine also exerts a protective effect on survival. This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Statistics plaquenil maculopathy Chloroquine & Hydroxychloroquine supporting chemo., Effect of hydroxychloroquine on the survival of patients with. Pharmacokinetics of chloroquineSpilled water on plaquenilChloroquine treatement ich per gallonSide effects of plaquenil depression Hydroxychloroquine Sulfate drug usage statistics for the United States 2007 - 2017. Statistics include drug synonyms and therapeutic classes, including Hydroxychloroquine Sulfate, Plaquenil, Antirheumatic Agent. Hydroxychloroquine Sulfate - Drug Usage Statistics.. Hydroxychloroquine-Induced Retinal Toxicity - American.. Recommendations on Screening for Chloroquine and.. The presence of bull’s-eye maculopathy indicates the disease has been progressing for years, resulting in foveal thinning and likely vision loss. 8 SD-OCT is a highly sensitive and reproducible imaging modality used in the detection of Plaquenil retinal toxicity. The preferential loss of photoreceptor IS/OS junction makes SD-OCT an ideal tool. Bull’s Eye Retinopathy Early macular toxicity can cause stippling or mottling of the RPE Next, granular pigmentation and loss of the normal foveal reflex can occur It’s believed but not proven that if early macular changes are detected and the medication is stopped, any toxicity that has occurred can be reversed.1 If the maculopathy continues to progress, concentric zones of. Dec 04, 2014 Hydroxychloroquine HCQ is an anti-malarial medication that has in recent times been utilized as treatment for a variety of autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus, and other inflammatory and dermatologic conditions.