Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Which is better for ra plaquenil or methotrexate Ocular issue plaquenil Hydroxychloroquine for leg cramps Chloroquine osteoarthritis Of cells at the back of the eye. This is known as retinal toxicity or retinopathy. Overall, around seven patients out of every 100 taking hydroxychloroquine for more than five years may develop retinopathy that can be detected with specialised tests. The risk is much higher in patients who have been taking the drug for 20 years or more. In these We now know that bull’s-eye maculopathy is a late finding and may be associated with vision loss. Asians have a slightly different clinical presentation 3-4. Several recent studies have shown that instead of the classic perifoveal changes typical of hydroxychloroquine toxicity, Asians with retinal toxicity have a more peripheral pattern. Hydroxychloroquine is a well-tolerated medication for various rheumatologic and dermatologic conditions. Its main side effects are gastrointestinal upset, skin rash, headache, and ocular toxicity1. Within the eye, hydroxychloroquine can adversely impact the cornea, ciliary body, and retina1 Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Eye toxicity hydroxychloroquine The Risk of Retinal Toxicity with Plaquenil, Hydroxychloroquine And Chloroquine Screening 2016 AAO. Hair loss plaquenilPlaquenil storage water or fat solubleMylan hydroxychloroquine However, Hydroxychloroquine and chloroquine CQ have been associated with irreversible visual loss due to retinal toxicity. Hydroxychloroquine retinal toxicity is far more common than previously. Hydroxychloroquine retinopathy Eye. Hydroxychloroquine toxicity - EyeWiki. Plaquenil Side Effects Common, Severe, Long Term -. If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Toxicity from hydroxychloroquine may be seen in two distinct areas of the eye, the cornea, and the macula. The cornea may become affected relatively commonly by an innocuous vortex keratopathy characterized by whorl-like corneal epithelial deposits. On examination, a telltale sign of hydroxychloroquine toxicity is a bilateral change in the retinal pigment epithelium of the macula that gives the commonly described appearance of a bull’s-eye. This is a late finding, however, and too late for screening to be useful.