The disease is transmitted by the bite of a mosquito. The Chloroquine drug is also used for treating liver disease caused by protozoa. Plaquenil elevated liver enzymes Plaquenil reduces preeclampsia Lupus on plaquenil CHLOROQUINE PHOSPHATE, USP DESCRIPTION ARALEN, chloroquine phosphate, USP, is a 4-aminoquinoline compound for oral administration. It is a white, odorless, bitter tasting, crystalline substance, freely soluble in water. ARALEN is an antimalarial and amebicidal drug. The first-line treatment for chloroquine-resistant CQR malaria – sulfadoxine–pyrimethamine – rapidly met with resistance and is also becoming increasingly ineffective. •Failure of P. falciparum clinical treatment resulting from confirmed in-vivo parasite resistance has now been documented for several current antimalarial drugs. Chloroquine enters the red blood cell by simple diffusion, inhibiting the parasite cell and digestive vacuole. Chloroquine then becomes protonated to CQ2+, as the digestive vacuole is known to be acidic pH 4.7; chloroquine then cannot leave by diffusion. However, it has no effect on pre and exo-erythrocytic phases of the parasite and does not prevent relapses in vivax and ovale malaria. It is rapidly acting erythrocytic schizonticide; controls most clinical attacks in 1-2 days with disappearance of parasites from peripheral blood. Chloroquine ineffective on exo CDC - Malaria - Malaria Worldwide - How Can Malaria Cases and., Current Trends of Anti-malarial Drugs Does hydroxychloroquine cause weight lossShortness of breath related to plaquenilChloroquine phosphate pricePlaquenil pronounceA patient recieving plaquenil therpay but tells the nurse Chloroquine resistance Chloroquine is ineffective in almost all malaria endemic countries In India chloroquine resistance was first detected in 1973 in Assam. Severe in northeast and southeastern regions of India with high morbidity and mortality. DRUG RESISTANT MALARIA CURRENT STATUS. Chloroquine - Wikipedia. Antimalarial Drugs - BrainKart. Learn more about Chymotrypsin uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain Chymotrypsin Chloroquine phosphate may cause an upset stomach. Take chloroquine phosphate with food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use chloroquine phosphate exactly as directed. Do not use more or less of it or use it more often than prescribed by your. Provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.