She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation. Plaquenil pregnancy complications Does hydroxychloroquine decrease human anti-chimeric antibody Oct 23, 2006 The initial diagnosis was corneal verticillata O. S. and suspected hydroxychloroquine maculopathy O. U. The old RPE detachment was suspected to be secondary to chronic steroid use.18,19 Treatment and Follow-Up We monitored the conditions and educated the patient on the ocular side effects of hydroxychloroquine and steroid use. Hydroxychloroquine can be prescribed for either prevention or treatment of malaria. This fact sheet provides information about its use for the prevention of malaria infection associated. with travel. Center for Global Health Division of Parasitic Diseases and Malaria. Who can take hydroxychloroquine? Hydroxychloroquine can be prescribed to adults Used for treatment of malignant glioma & metastatic breast cancer Three types of retinal toxicity 1. Pigmentry maculopathy with marked decreased VA, and abnormal electrophysiologic testing. 2. Cotton wool spots, intraretinal hemorrhages, macular exudates & optic neuropathy with disc swelling 3. Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use. Plaquenil maculopathy treatment Hydroxychloroquine Plaquenil Toxicity and Recommendations., Medicines for the Prevention of Malaria While Traveling. Plaquenil how to takeWhat side effects does plaquenil have on your teethWhat symptoms does plaquenil treat Patients with possible hydroxychloroquine retinopathy should continue drug treatment. This will reduce the risk of inappropriate treatment cessation. GPP Patients with one abnormal test result on retinal imaging SD-OCT & widefield FAF but normal visual fields including 30-2 protocol if appropriate should return for annual review as per the Hydroxychloroquine and Chloroquine Retinopathy.. Drug induced maculopathy - EyeWiki. RCOphth guideline Hydroxychloroquine and Chloroquine.. Hydroxychloroquine retinopathy, it is important you ask your GP or specialist to refer you for screening. Progression of retinopathy. In most cases it is expected that stopping the hydroxychloroquine treatment will stop the. retinopathy worsening. If the condition does progress, a person may. experience significant loss of vision over time. Aug 06, 2014 Hydroxychloroquine, sold under the brand name Plaquenil Sanofi-Aventis, is an antimalarial drug that has gained widespread use in treating various autoimmune diseases, including systemic lupus erythematosus and rheumatoid arthritis. 1 By some estimates, more than 150,000 patients are on long-term therapy with this medication in America alone. 2 Retinal toxicity associated with HCQ use is. Plaquenil or hydroxychloroquine is under the quinolone family. These medications are initially used in the prophylaxis and treatment of malaria. Plaquenil has replaced chloroquine because it produces less retinal side effects.