The condition often accompanies other immune system disorders, such as rheumatoid arthritis and lupus. In Sjogren's syndrome, the mucous membranes and moisture-secreting glands of your eyes and mouth are usually affected first — resulting in decreased tears and saliva. Your immune system mistakenly attacks your body's own cells and tissues. Plaquenil dose based on weight Plaquenil toxicity screening Hydroxychloroquine liver toxicity alcohol Plaquenil for chronic hives For many patients with Sjogren's, Plaquenil hydroxychloroquine has long been the go to drug that their doctors prescribe. It is often the first line of attack before other more aggressive therapies are added such as methotrexate or rituximab that have bigger impacts on the immune system. Apr 17, 2014 I completely agree with Lynnwood that plaquenil helps stop the progression of your disease, so the longer you wait the worse your Sjogren's becomes. Plaquenil is a fairly benign medication and was originally developed to protect against malaria. Later it was found to help autoimmune diseases. It can be months before you get relief with plaquenil. Sjogren's syndrome is an autoimmune disorder in which immune cells attack and destroy the exocrine glands that produce tears and saliva. It also associated with rheumatic disorders such as rheumatoid arthritis, and it is rheumatoid factor positive in 90 percent of cases. Dry eyes, Sjogrens and Plaquenil. Certain genes put people at higher risk of the disorder, but it appears that a triggering mechanism — such as infection with a particular virus or strain of bacteria — is also necessary. Scientists aren't certain why some people develop Sjogren's syndrome. Plaquenil and sjogren's syndrome Sjogren's syndrome - Diagnosis and treatment - Mayo Clinic, Treatment/Plaquenil - What does plaquenil do to the bodyChloroquine as antiamoebicPlaquenil toxicity symptoms liverHydroxychloroquine usmle mechanism of actionMode of action of chloroquine Sjogren’s syndrome may also be confused with diseases, such as viral infections drug side effects e.g. antihypertensives, antidepressant or antihistamines. Other diseases may also cause salivary gland enlargement, such as viral infections, sarcoidosis a chronic lung disease, and diabetes. Sjogren’s Syndrome and Lupus Sjogren's Treatment TheraLife. Dry eyes, Sjogrens and Plaquenil. DailyStrength. Sjogrens Mayo Clinic Connect. Reviews and ratings for hydroxychloroquine when used in the treatment of sjogren's syndrome. 45 reviews submitted. User Reviews for Hydroxychloroquine to treat Sjogren's Syndrome. Also known as Plaquenil. The other immune drugs have scary side effects almost worth waiting for a flare and dealing with steroids then the side effects of. User Reviews for Plaquenil to treat Sjogren's Syndrome. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Hydroxychloroquine Plaquenil, an antimalarial drug used in lupus and rheumatoid arthritis, may be helpful in some patients with Sjögren's syndrome by reducing joint pain and rash experienced by some patients.