It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Plaquenil and doxycycline interaction Chloroquine regimen Plaquenil high blood pressure Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Rarely, hydroxychloroquine can affect the bone marrow leading to reduced white blood cells leukopenia or platelets thrombocytopenia and abnormal red blood cells anemia. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Hydroxychloroquine is used in the treatment of malaria, rheumatic disorders, and systemic lupus erythematosus. 8 Many side effects have been reported associated with the use of hydroxychloroquine. Among these side effects, there is a particular concern regarding the development of cardiomyopathy and thrombocytopenia. 9, 10 This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. Hydroxychloroquine thrombocytopenia side effects Hydroxychloroquine Side Effects, Dosage, Uses, and More, Plaquenil Side Effects Common, Severe, Long Term - Chloroquine toxicityChloroquine side effects long termChloroquine pancreatic cancerChloroquine resistant malaria treatment For the Consumer. Continuing ringing or buzzing or other unexplained noise in the ears. feeling of constant movement of self or surroundings. irritability. nausea. nervousness. nightmares. sensation of spinning. shakiness and unsteady walk. uncontrolled eye movements. unsteadiness, trembling, or. Hydroxychloroquine Side Effects -. A case of thrombocytopenia associated. -. Hydroxychloroquine Indications, Side Effects, Warnings.. Abstract. Hydroxychloroquine is used in the long-term therapy of systemic lupus erythematosus SLE. Although considered to be a safe treatment, side effects have been documented. An uncommon side effect is thrombocytopenia. In order to establish the diagnosis of thrombocytopenia secondary to Hydroxychloroquine. One of the most significant side effects of the drug is its possibility of causing eye problems resulting in blurred or decreased vision. The most common issue is damage to the retina. It can impair your color vision or damage the retinal cells particularly in the area right around. Summary Hyperglycemia is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years, also take medication Methotrexate, and have Osteoporosis. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food.