Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Urinary side effects of hydroxychloroquine Using hydroxychloroquine and leflunomide together Chloroquine Phosphate is the phosphate salt of chloroquine, a quinoline compound with antimalarial and anti-inflammatory properties. Chloroquine is the most widely used drug against malaria, except for those cases caused by chloroquine resistant Plasmodium falciparum. Antimalarial therapy is considered a mild disease modifying therapy in the management of inflammatory arthritis, in particular for Rheumatoid arthritis. The drug is available in several forms. These side effects were seen most often in patients receiving large doses for treatment of lupus or rheumatoid arthritis; however, such reactions have been noted in patients taking therapeutic doses for short periods. Symptoms often resolved over time with a reduction of the dose or discontinuation of chloroquine. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine phosphate for rheumatoid arthritis Anti-malaria drug being tested for efficacy against COVID-19, Antimalarials in Arthritis by drdoc on-line Plaquenil risksHydroxychloroquine side effects medbulletsIcd 10 coding for plaquenil usePlaquenil and stroke What Conditions Does This Treat? Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions. RA and Hydroxychloroquine How Effective is it for Rheumatoid Arthritis.. Chloroquine Side Effects Common, Severe, Long Term.. Chloroquine Oral Route Proper Use - Mayo Clinic. Following a single dose, chloroquine may be detected in plasma for more than four weeks. Mean bioavailability from tablets of chloroquine phosphate is 89%. Chloroquine is widely distributed in body tissues such as the eyes, kidneys, liver, and lungs where retention is prolonged. The value of chloroquine in rheumatoid disease a four-year study of continuous therapy. Can Med Assoc J. 1957 Aug 1;77 3182–194. COHEN AS, CALKINS E. A controlled study of chloroquine as an antirheumatic agent. Arthritis Rheum. 1958 Aug;1 4297–312. DUTHIE JJ, THOMPSON M, WEIR MM, FLETCHER WB. Plaquenil hydroxychloroquine and Aralen chloroquine phosphate are antimalarial medications used to treat or prevent malaria, a disease caused by parasites, which enter the body through the bite of a mosquito. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Aralen is also used to treat infections caused by amoebae.