Chloroquine chemistry

Discussion in 'Canada Pharmacy' started by videostar, 05-Mar-2020.

  1. Lisitsa Guest

    Chloroquine chemistry

    It will look at – in detail – quinine and quinine-related drugs. In a previous article, we briefly described malaria and artemisinin as a lead compound for new antimalarials.

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    Chloroquine is a 4-aminoquinoline compound that has been used extensively for the treatment and prevention of malaria Fig. 7.2. Despite the spread of chloroquine resistance against P. falciparum in some parts of the world, it remains the drug of choice for both chemoprophylaxis and uncomplicated malaria treatment of P. vivax, P. ovale, and P. malariae infections in areas where resistance is not known to occur. Aralen chloroquine is an antimalarial drug used for the treatment of malaria and extraintestinal amebiasis. Common side effects are reduced hearing, tinnitus, nausea, vomiting, and diarrhea. Dosage, drug interactions, and pregnancy and breastfeeding safety are provided. Chemistry Stack Exchange is a question and answer site for scientists, academics, teachers, and students in the field of chemistry. Can we get chloroquine from 4-amino-7-chloroquinoline 7-chloroquinolin-4-amine by adding 4-chloro-N,N-diethylpentan-1-amine $. That would be the synthesis of chloroquine from 4,7-dichloroquinoline and 4.

    Understanding the chemistry of these compounds also, as it happens, makes it much easier to comprehend the pharmacology and therapeutic management of malaria itself. We now turn our attention to the other antimalarial drugs.

    Chloroquine chemistry

    Structure Activity Relationship of CHLOROQUINE, Aralen chloroquine Malaria Drug Side Effects & Dosage

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  3. Synthesis of stable isotope-labeled chloroquine and amodiaquine and their metabolites. Journal of Labelled Compounds and Radiopharmaceuticals 2019, 62 5, 230-248. DOI 10.1002/jlcr.3721.

    • CHLOROQUINE MANUFACTURE Industrial & Engineering Chemistry.
    • Organic chemistry - Synthesis of chloroquine from 4-amino..
    • Chloroquine phosphate C18H32ClN3O8P2 - PubChem.

    Chloroquine, introduced into medicine in the 1940s, is a member of an important series of chemically related antimalarial agents, the quinoline derivatives. Chloroquine is administered orally as chloroquine phosphate. Data from NIST Standard Reference Database 69 NIST Chemistry WebBook; The National Institute of Standards and Technology NIST uses its best efforts to deliver a high quality copy of the Database and to verify that the data contained therein have been selected on the basis of sound scientific judgment. Now that chloroquine is in the news everywhere, I thought it might be interesting to have a closer look at the compound. The first part of this post will be chemistry-heavy, further down we'll get into the pharmacology and medical uses. Chloroquine's fame is as an antimalarial drug, and the h

  4. oleggggg XenForo Moderator

    Gunakan 1 gram chloroquine phosphate (600 mg base) diminum 1 kali selama 2 hari, kemudian diikuti oleh 500 mg chloroquine phosphate (300 mg base) diminum 1 kali/hari selama 2- 3 minggu Berikut adalah dosis klorokuin yang dianjurkan untuk anak-anak: Bayi dan anak-anak gunakan 8,3 mg chloroquine phosphate (300 mg base) diminum 1 kali/minggu pada hari yang sama tiap minggunya Bayi dan anak-anak dengan berat badan kurang dari 60 kg, gunakan obat oral: Beberapa pasien yang mengonsumsi chloroquine (klorokuin) dalam jangka waktu lama atau dosis tinggi melaporkan adanya kerusakan permanen pada retina mata. Interactions between Travel Vaccines & Drugs - Chapter 2. Chloroquine - Wikipedia Chloroquine Phosphate Bulk Uses, Side Effects.
  5. cwage Guest

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  6. ogonek2110 Well-Known Member

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