These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Plaquenil and wellbutrin Mefloquine hydrochloride chloroquine How long does it take for chloroquine to work Yes, plaquenil is difficult to adjust first, but after the first year of treatment and side effects, the benefits outweigh the problems. So, stick with it. In my opinion, the plaque nil is keeping the immune system regulated and the pain and other symptoms described will reduce. Lupus is not an illness without pain or sacrifice, but, it’s. Plaquenil is also used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Common side effects of Plaquenil include. nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. If you notice any other effects, check with your healthcare professional. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Plaquenil side effects stomach pain Plaquenil and stomach issues." Lupus Community - Support Group, Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Methotrexate plaquenilPlaquenil and eye photosensitivityHydroxychloroquine plaquenil 200mgHydroxychloroquine abbreviation Find information about common, infrequent and rare side effects of Plaquenil Oral. Common and Rare Side Effects for Plaquenil Oral. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Plaquenil and stomach pain DailyStrength. I have a problem. I was diagnosed on October 14, 2013 with UCTD. The Rheumatologist put me on Plaquenil. I started with just one pill per day because I sometimes have side effects from new drugs. After just 4 days on Plaquenil, I had severe stomach cramps, no appetite, GERD pain, diarrhea and a migraine. I've been taking Plaquenil for one month 1 x 200 mg. I should have taken 2 x 200 mg but from the beginning I had diarrhea and stomach pain. If I want to increase the Plaquenil my complaints get worse. Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used.