Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take chloroquine with all of your drugs and health problems. Layers of retina affected with plaquenil Chloroquine in lupus Teva chloroquine side effects Chloroquine resistance is associated with a decrease in the amount of chloroquine that accumulates in the food vacuole, the site of action for chloroquine. The mechanism for this decreased accumulation is controversial. Some studies have shown that the decrease in drug accumulation is due to an increase in drug efflux. A severe eye problem has happened with chloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. Oct 01, 2018 Mechanism of Action Chloroquine, a 4-aminoquinoline, is an anti-protozoal agent. The precise mechanism by which Chloroquine exhibits activity is not known. Chloroquine, may exert its effect against Plasmodium species by concentrating in the acid vesicles of the parasite and by inhibiting polymerization of heme. It can also inhibit certain. For all uses of chloroquine: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor. What is chloroquine mode of action Antimalarial drugs Mode of action and status of resistance, Chloroquine Indications, Side Effects, Warnings - Hydroxychloroquine 부작용Hydroxychloroquine chemoPlaquenil hot flashes Chloroquine and hydroxychloroquine are drugs derived from the quinoline molecule. Both are used as antimalarial blood schizonticides, and hydroxychloroquine is also frequently used as an antirheumatic. Their mechanism of action is not entirely understood. Chloroquine and hydroxychloroquine – Knowledge for medical.. Chloroquine - FDA prescribing information, side effects and uses. Chloroquine Oral Uses, Side Effects, Interactions, Pictures.. Action of the drug chloroquine Chloroquine should be used with caution in patients with known porphyria cutanea tarda. Chloroquine can be used to treat porphyria cutanea tarda, but in a very low dose 125 mg twice weekly as a dosage of 250 mg/day can trigger a porphyria crisis, which can be fatal. Chloroquine works best when you take it on a regular schedule. For example, if you are taking it once a week to prevent malaria, it is best to take it on the same day of each week. Make sure that you do not miss any doses. If you have any questions about this, check with your doctor.