Why chloroquine is given in liver abscess

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  1. zapor Moderator

    Why chloroquine is given in liver abscess


    -Suppressive therapy should continue for 8 weeks after leaving the endemic area. Approved indication: For the suppressive treatment of malaria due to Plasmodium vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: 300 mg base (500 mg salt) orally once a week Comments: -For prophylaxis only in areas with chloroquine-sensitive malaria -Prophylaxis should start 1 to 2 weeks before travel to malarious areas; should continue weekly (same day each week) while in malarious areas and for 4 weeks after leaving such areas.

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    In treatment of amoebic liver abscess, chloroquine may be used instead of or in addition to other medications in the event of failure of improvement with metronidazole or another nitroimidazole within 5 days or intolerance to metronidazole or a nitroimidazole. Jun 12, 2018 Amebic abscess should be treated with metronidazole, which will be curative in 90% of cases. Metronidazole should be initiated before serologic test results are available. Patients who do not respond to metronidazole should receive chloroquine alone or in combination with emetine or dehydroemetine. Thank you for your interest in spreading the word about The BMJ. NOTE We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail.

    Approved indication: For acute attacks of malaria due to P vivax, P malariae, P ovale, and susceptible strains of P falciparum CDC Recommendations: Chloroquine-sensitive uncomplicated malaria (Plasmodium species or species not identified): 600 mg base (1 g salt) orally at once, followed by 300 mg base (500 mg salt) orally at 6, 24, and 48 hours Total dose: 1.5 g base (2.5 g salt) Comments: -For the treatment of uncomplicated malaria due to chloroquine-sensitive P vivax or P ovale, concomitant treatment with primaquine phosphate is recommended. 60 kg or more: 1 g chloroquine phosphate (600 mg base) orally as an initial dose, followed by 500 mg chloroquine phosphate (300 mg base) orally after 6 to 8 hours, then 500 mg chloroquine phosphate (300 mg base) orally once a day on the next 2 consecutive days Total dose: 2.5 g chloroquine phosphate (1.5 g base) in 3 days Less than 60 kg: First dose: 16.7 mg chloroquine phosphate/kg (10 mg base/kg) orally Second dose (6 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Third dose (24 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Fourth dose (36 hours after first dose): 8.3 mg chloroquine phosphate/kg (5 mg base/kg) orally Total dose: 41.7 mg chloroquine phosphate/kg (25 mg base/kg) in 3 days Comments: -Concomitant therapy with an 8-aminoquinoline compound is necessary for radical cure of malaria due to P vivax and P malariae.

    Why chloroquine is given in liver abscess

    Drainage of Hepatic, Subphrenic, and Subhepatic Abscesses., Liver Abscess Medication Antibiotics, Antifungal agents

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  6. CHLOROQUINE HYDROCHLORIDE INJECTION USP Usual adult and adolescent dose Malaria treatment Intramuscular, initially 200 to 250 mg 160 to 200 mg base, repeated in six hours if necessary, not to exceed 1 gram 800 mg base in the first twenty-four hours {06}. Liver abscess, amebic treatment

    • Chloroquine Hydrochloride Drug Information, Professional.
    • Chloroquine in the Treatment of Amoebic Liver Abscess The BMJ.
    • Amoebiasis Diagnosis, symptoms, complications and management.

    Chloroquine has a high affinity for tissues of the parasite and is concentrated in its cytoplasm. As a weak base, it increases the pH of the intracellular lysosome and endosome. A more acidic medium in these organelles is needed for the parasite to affect mammalian cells. As a result, chloroquine inhibits growth and development of parasites. The data of this case were graciously supplied by Dr. F. Murgatroyd and Dr. N. H. Fail-ley of London. 316 Chloroquine for Hepatic Amebiasis—Conan Also given during the second five days were irrigations of the abscess cavity twice daily with 40 ml. of 0.1 per cent proflavine. An additional 30 patients were treated without randomization. Chloroquine was given according to the standard protocol at Los tangeles County-University of Southern California Medical Center, which is 500 mg daily for 10 weeks, whereas metronidazole was given in a dose of 750 mg three times daily for 10 days.

     
  7. ara rules User

    Plaquenil is the brand name for the prescription drug hydroxychloroquine. Plaquenil Hydroxychloroquine Sulfate - Sanofi Plaquenil hydroxychloroquine sulfate dose, indications, adverse. Plaquenil Side Effects - Treato
     
  8. SereGaZ User

    Hydroxychloroquine Side Effects, Dosage, Uses, and More If you develop these symptoms, call 911 or go to the nearest emergency room. Don’t take this drug again if you’ve ever had an allergic reaction to it. Taking it again could be fatal cause death.

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  9. turbaza New Member

    Buy Malaria Tablets Online from UK Pharmacy - Dr Fox Anti-malaria tablets are prescription only except chloroquine or chloroquine with proguanil – our doctors will issue the prescription online direct to our pharmacy. Dr Fox Pharmacy supplies medicines only for adults over 18 years. Further information about malaria tablets for children. Comparing malaria tablets

    CDC - Malaria - Travelers - Malaria Information and.