Keep in mind that most people with Sjogren's stay healthy and don't have serious problems. You should be able to keep doing all the things you love to do without making many changes. Hydroxychloroquine bluelight Can hydroxychloroquine cause dry eyes Hydroxychloroquine cream Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Do you think the Raynaud's phenomenon is related to my dry eyes? I ask this because so far these seem to be the only two confirmed issues that point to Sjogren's and the former started occurring many, many years ago, while the dry eyes about three years ago. Do you think it is the right stage of diagnosis of Sjogren's to take Plaquenil? Aug 28, 2012 plaquenil causing dry eyes to be worse. anybody have this? on August 28, 2012, PM i just read that plaquenil can cause eyes to get more dry--- wow. i am now wondering if that is why my eyes have gotten worse-it seems since i have been on plaquenil. its been years but i wonder. Conditions like this are called autoimmune diseases. Sjogren's causes your immune system to go haywire and attack healthy cells instead of invading bacteria or viruses. Plaquenil causes dry eyes How lupus affects the eyes Lupus Foundation of America, Dry eyes, Sjogrens and Plaquenil. DailyStrength Hydroxychloroquine vs hydroxychlorPlaquenil and fatigueChloroquine phosphate overdose Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Plaquenil Side Effects Common, Severe, Long Term -. Plaquenil causing dry eyes to be worse. anybody have this?. Hydroxychloroquine Plaquenil Toxicity and.. Plaquenil is a drug used to treat Rheumatoid Arthritis and Systemic Lupus Erythematosis. It is a very good drug and gives many patients significant relief from their symptoms. Plaquenil related eye complications are not common. Plaquenil can produce pigment changes in the macula of the retina. Summary Dry mouth is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Enbrel, and have Osteoporosis. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration. Sjögren's syndrome with gland inflammation resulting dry eyes and mouth, etc. that is not associated with another connective tissue disease is referred to as primary Sjögren's syndrome. Sjögren's syndrome that is also associated with a connective tissue disease, such as rheumatoid arthritis, systemic lupus erythematosus, or scleroderma, is referred to as secondary Sjögren's syndrome.