Im thinking a rash stays a lil & doesnt come for 10 minutes & then goes. I get facial flushing BUT when I was at the rhemy the other day, I was trying to explain to him how I get this. He said "you have it right now" But said it wasnt the ONLY show up during a FLARE because mine seems to come & go ALL the time. Hydroxychloroquine plaquenil ingredients Hydroxychloroquine interaction Find information about common, infrequent and rare side effects of Plaquenil Oral. How to use Plaquenil Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. The fact that you do have a butterfly rash and are responding to Plaquenil would be a better indication that you do have lupus, though most dr.s will not give a true diagnosis without one of the more specific lupus tests being positive. You could develope abnormal test results in the future or you may not. I've read at least a dozen online articles to try to figure things out, and I'm even more confused after reading because some of them contradict the others! Also when im cooking, I ALWAYS get it from being in/out of the oven......... THXXXX __________________Rachel Hi Rachel, I'm no expert at all...main reason I'm replying to you is because I've wondered the same thing myself. Does plaquenil take away the butterfly rash Lupus Rash Signs, Symptoms and Natural Treatments, Plaquenil Oral Uses, Side Effects, Interactions, Pictures. Plaquenil side effects sensitive gumsChloroquine panreatic cancer As noted, the most common antimalarial used is Plaquenil hydroxychloroquine, which is dosed by weight and used for persistent rashes. Evidence suggests that early use may delay systemic onset of lupus. Rashes, Skin Care and Cutaneous Lupus What You Should Know. Responding to plaquenil is it lupus? DailyStrength. What are the 11 signs of lupus? - WebMD. Plaqunil rash. Support Forums. How does Plaquenil work? Surprisingly, the reason for its success in lupus still remains somewhat mysterious. It has a wide variety of known effects – aspirin-like anti-inflammatory, mild immunosuppressive and mild cholesterol lowering amongst others. Perhaps an important property is that of sun-protection. ACLE generally causes redness over the cheeks and nose. The redness is often called a “butterfly rash.” It fades over a few weeks and does not leave scarring. The rash is usually seen in people with systemic lupus who are having a flare. It can be brought on or worsened by exposure to sunlight. People with lupus must protect themselves from the sun. The plaquenil may or may not make the butterfly rash go away. There is no way to predict. Typically plaquenil takes 4 to 6 months to take full effect in controlling systemic lupus. It makes you a little less photosensitive as well. Please make sure you have a baseline field of vision test. It is just precautionary, but you do need a baseline.